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1.
Emergency department visits respond nonlinearly to wildfire smoke.
Proc Natl Acad Sci U S A
; 120(39): e2302409120, 2023 09 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-37722035
2.
SAR inspired by aldehyde oxidase (AO) metabolism: Discovery of novel, CNS penetrant tricyclic M4 PAMs.
Bioorg Med Chem Lett
; 29(16): 2224-2228, 2019 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31248774
3.
Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amides.
Bioorg Med Chem Lett
; 27(13): 2990-2995, 2017 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28522253
4.
Challenges in the development of an M4 PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs.
Bioorg Med Chem Lett
; 27(2): 171-175, 2017 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27939174
5.
Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides.
Bioorg Med Chem Lett
; 27(23): 5179-5184, 2017 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29089231
6.
Optimization of M4 positive allosteric modulators (PAMs): The discovery of VU0476406, a non-human primate in vivo tool compound for translational pharmacology.
Bioorg Med Chem Lett
; 27(11): 2296-2301, 2017 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28442253
7.
Selective inhibition of KCC2 leads to hyperexcitability and epileptiform discharges in hippocampal slices and in vivo.
J Neurosci
; 35(21): 8291-6, 2015 May 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-26019342
8.
Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition.
Bioorg Med Chem Lett
; 26(17): 4282-6, 2016 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27476142
9.
Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core.
Bioorg Med Chem Lett
; 26(13): 3029-3033, 2016 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27185330
10.
How Does Risk Selection Respond to Risk Adjustment? New Evidence from the Medicare Advantage Program.
Am Econ Rev
; 104(10): 3335-64, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-29533567
11.
Why Does the Inflation Reduction Act Exclude Expensive Cancer Treatments in Price Negotiations?
JCO Oncol Pract
; 20(2): 254-261, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38060993
12.
The patient-centered medical home: an evaluation of a single private payer demonstration in New Jersey.
Med Care
; 51(6): 487-93, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23552431
13.
Corrigendum to "Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides" [Bioorg. Med. Chem. Lett. 27(23) (2017) 5179-5184].
Bioorg Med Chem Lett
; 28(17): 3014, 2018 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30076050
14.
Biosimilar Competition and Payments in Medicare: The Case of Trastuzumab.
JCO Oncol Pract
; 19(4): e476-e483, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36638330
15.
Technology enabled home-based cardiac rehabilitation among women with cardiovascular disease: A longitudinal cohort study.
Int J Cardiol Cardiovasc Risk Prev
; 19: 200226, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-38093813
16.
A Chemical Strategy toward Novel Brain-Penetrant EZH2 Inhibitors.
ACS Med Chem Lett
; 13(3): 377-387, 2022 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35300079
17.
Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiology.
J Biol Chem
; 285(22): 17054-64, 2010 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-20356837
18.
Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules.
Cancer Res
; 81(8): 2002-2014, 2021 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33632898
19.
Identification of anabolic selective androgen receptor modulators with reduced activities in reproductive tissues and sebaceous glands.
J Biol Chem
; 284(52): 36367-36376, 2009 Dec 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-19846549
20.
Veterans' Labor Force Participation: What Role Does the VA's Disability Compensation Program Play?
Am Econ Rev
; 105(5): 131-6, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-29543407